Senior Lecturer

E-mail : shruti.jain@juit.ac.in

office:(+91)01792-239245 (O)

Education:

Pursuing Ph.D. from Jaypee University of Information Technology Waknaghat, Solan

M.Tech 

Research Interests

Bio Simulator based on VHDL and AI modeling: Designing, Testing, Implementation and Application in System Biology.
My research is based on VHDL and AI modeling for Apoptosis and Cell survival. The work examines signaling networks that control the death decision treated with combinations of three primary signals; the pro-death cytokine, tumor necrosis factor-α (TNF), and the pro-survival growth factors, epidermal growth factor (EGF) and insulin. The system output is typically a phenotypic readout (death or survival); however, it can also be determined by measuring “early” signals that perfectly correlate with the death/ survival output. Examples of such early signals include phosphatidylserine exposure, membrane permeability, nuclear fragmentation and caspase substrate cleavage.

The model for cell death and cell survival have been implemented using Very High Speed Integrated Circuit Hardware Description Language (VHDL) (Xilinx Tool) and MATLAB simulator taking three input signals: Tumor necrosis factor-α (TNF), Epidermal growth factor (EGF) and Insulin. We are developing Artificial Neural Networks (ANN) for modeling cell death and cell survival. We are also developing bio-simulator that can be used for prediction of status of the cell leading to cell survival/ death giving chemotherapy and radiotherapy treatment.

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Brief Background :

Biography

Lecturer, Haryana Engineering College (2004), EVENT CO-ODINATOR,Brain Storm Committee (Technical fest)in Azzaro (2005), In charge of “Technopreneur Promotion Programe TePP” Electronics Research Development & facilities centre, HARTRON Symposium (2007), Head Pinnacle.. Beyond The Heights, Electronics & Communication Society (2007), Lecturer Ambala College of Engineering & Applied Research (2008), Presently Senior Lecturer at Jaypee University of Information Technology, Waknaghat .

Publications:

PAPER PUBLISHED:

JOURNALS

• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “Petri net Implementation of Cell Signaling for Cell Death”, International Journal of Pharma and Bio Sciences (IJPBS), V(1)2, 2010.(ISSN 0975-6299)

• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “Caspase : Leads to Apoptosis using VHDL and SPICE”, International Journal of Electronics and Computers, 2(1): 9-17, January-June 2010.(ISSN 0975-3796)

• Shruti Jain, Sunil V. Bhooshan, Pradeep K. Naik, “Model of Mitogen Activated Protein Kinases for Cell Survival/Death and its Equivalent Bio-Circuit”, Current Research Journal of Biological Sciences (CRJBS), 2(1):59-71, 2010. (ISSN : 2041-0778)
• Shruti Jain, Pradeep K. Naik, Computational Modeling of Cell Survival using VHDL, BVICAM's International Journal of Information Technology (BIJIT), Vol 2: 47-51 January-June 2010 (ISSN 0973-5658).
• Shruti Jain, Pradeep K. Naik, Rohit Sharma, A Computational Modeling of cell survival/ death using VHDL and MATLAB Simulator, Digest Journal of Nanomaterials and Biostructures (DJNB), 4 (4): 863- 879, 2009, (ISSN 1842 – 3582).
• Shruti Jain, Pradeep K. Naik, Rohit Sharma, A Computational Modeling of Apoptosis Signaling using VHDL and MATLAB Simulator, International Journal of Information and Communication Technology  (IJICT), 2(1-2):7-12, January-June 2009 (ISSN 0973-5836).
• C.C. Tripathi, Shruti Jain, Pawan Joshi, S.C. Sood & Dinesh Kumar, Development of Low Cost Set Up for Anodic Bonding and its Characterization, Indian Journal of Pure & Applied Physics, Vol.46, Oct 2008, pp 738-743.

 CONFERENCES 

• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “A System Model for Cell Death using Fuzzy Logic and SPICE”, February 26-27, 2010, pp 756-760, ICWET 2010, International Conference and Workshop on Emerging Trends in Technology, Thakur College of Engineering & Technology,Mumbai, India.

• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “Petri nets – an Application in Digital Circuits”, February 26-27, 2010, pp 9, ICWET 2010, International Conference and Workshop on Emerging Trends in Technology, Thakur College of Engineering & Technology,Mumbai, India.
• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “BiCMOS Implementation of Cell Signaling for Cell Survival/Death”, February 9-10,2010, pp 23-26, ICSAP, 2010 International Conference on Signal Acquisition and Processing, Banglore, India
• Shruti Jain, Pradeep K. Naik, Sunil V. Bhooshan, “Design of Fuzzy Membership Functions using SPICE”, January 9-10, 2010, pp 317-321, RTSCIT09, International Conference  on Recent Trends in Soft Computing and Information Technology, Corporate Institute of Science and Technology, Bhopal, Madhya Pradesh, India.
• Shruti Jain, Pradeep K. Naik, C.C. Tripathi, “A Computational Model for Cell Survival and Fabrication of Transistor”, October 23-24, 2009, pp 39-43, WECON 2009 International Conference on Wireless Networks and Embedded Systems, Chitkara Institute of Engineering and Technology, Chandigarh-Patiala National Highway, Patiala, India
• Shruti Jain, Pradeep K. Naik, “Synthetic Biology : Towards Digital Circuits”, October 23-24, 2009, pp 100-102,  WECON 2009 International Conference on Wireless Networks and Embedded Systems, Chitkara Institute of Engineering and Technology, Chandigarh-Patiala National Highway, Patiala, India
• Shruti Jain, P.K. Naik , D. S. Chauhan, Rohit Sharma, “Computational Modeling of Cell Survival/ Death using MATLAB simulator”, April 27-29, 2009, pp 64-68, 6th International Conference on Information Technology : New Generations ITNG 2009, Las Vegas, Nevada, USA. http://doi.ieeecomputersociety.org/10.1109/ITNG.2009.101
• Shruti Jain, P.K. Naik , D. S. Chauhan, Rohit Sharma, “A System Model of Apoptosis and Survival Signaling”, March 6-7, 2009, pp 82-86, IEEE International Advanced Computing Conference IACC'09, Thapar University, Patiala, Punjab, India.

• Shruti Jain, P.K. Naik , D. S. Chauhan, Rohit Sharma,  “Computational Modeling of Apoptosis using VHDL and Bio circuits”, February 14-16, 2009, pp 62-67, 3rd International Conference on Intelligent Systems & Networks (IISN-2009), Institute Of Science and Technology, KLAWAD (ISTK), Ambala- Jagadhri Road, Distt. Yamuna Nagar, Haryana, India.
• Shruti Jain,  S. C. Sood, C. C. Tripathi , “Modeling of Direct Silicon Fusion Wafer Level Packaging”, December 26-27, 2008, pp 934-938 International conference on Advanced Computing Technologies (ICACT '08), Hyderabad, India.

• Shruti Jain, S. C. Sood, C. C. Tripathi, “Modeling of silicon fusion wafer level packaging for RF MEMS switches", December 19-21,2007, pp114 of MNNA 2007, Indo Australian Symposium on Multifunctional Nano materials Nanostructures and Applications, Department of Physics and Astrophysics, University of Delhi, Delhi.
• Shruti Jain, " Investigation of silicon to silicon wafer bonding", November 16-17,2007 pp 28 (C-35) of ISSS-MEMS 2007, 2nd ISSS National conference on MEMS, Micro sensors, Smart Materials, Structures and Systems, Central Electronics Engineering Research Institute, Pilani & Birla Institute of Technology and Science, Pilani-333031, Rajasthan.
• Shruti Jain, “Design & Development of Capacitive Pressure Sensor for Industrial application using Dissolved Wafer Process & MEMS Technology” June 7-9, 2007 HARMST-007, 7th Internatioanl Workshop On High –Aspect- Ratio Microstructure Technology Besancon, France.
• Shruti Jain, “Low Voltage Anodic Bonding for the Fabrication Of MEMS Devices”, Feb16-18th 2007 pp155-159 of EMTM2N-2007, International Conference on Emerging Mechanical Technology- Macro to Nano, Birla Institute Of Technogy & Science, Pilani, Rajasthan.

NATIONAL CONFERENCES: 12 papers

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